Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

PRODUCT NAME

QINGDAO RUBACE DTDM

NFPA

PRODUCT USE

Used as a staining protector in rubber and in the vulcanisation of rubber. Also used as a
fungicide.

SYNONYMS

"rubber chemical"

Section 2 - HAZARDS IDENTIFICATION

CANADIAN WHMIS SYMBOLS

EMERGENCY OVERVIEW

RISK

Irritating to skin.

POTENTIAL HEALTH EFFECTS

ACUTE HEALTH EFFECTS

SWALLOWED

  Although ingestion is not thought to produce harmful effects, the material may still be damaging to the health of the individual following ingestion, especially where pre-  existing organ (e.g. liver, kidney) damage is evident. Present definitions of harmful or toxic substances are generally based on doses producing mortality (death) rather than those producing morbidity (disease, ill-health). Gastrointestinal tract discomfort may produce nausea and vomiting. In an occupational setting however, ingestion of insignificant quantities is not thought to be cause for concern.  Considered an unlikely route of entry in commercial/industrial environments.  

EYE

  Although the material is not thought to be an irritant, direct contact with the eye may produce transient discomfort characterized by tearing or conjunctival redness (as with windburn).  The material may be irritating to the eye, with prolonged contact causing inflammation. Repeated or prolonged exposure to irritants may produce conjunctivitis.  

SKIN

  This material can cause inflammation of the skin oncontact in some persons.  Skin contact is not thought to have harmful health effects, however the material may still produce health damage following entry through wounds, lesions or abrasions.  Sensitization may result in allergic dermatitis responses includingrash, itching, hives or swelling of extremities.  The material may cause skin irritation after prolonged or repeated exposure and may produce on contact skin redness, swelling, the production of vesicles, scaling and thickening of the skin.  

INHALED

  The material is not thought to produce adverse health effects or irritation of the respiratory tract (as classified using animal models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable control measures be used in an occupational setting.  

CHRONIC HEALTH EFFECTS

  Principal routes of exposure are usually by skin contact and inhalation of generated dust.  The product may liberate free amines, some of which are highly irritating.  This product may react with nitrosating agents to form N-nitrosomorpholine  which is a suspected carcinogen. [Monsanto]  Long term exposure to morpholine and some of its congeners may produce liver and kidney damage. Obvious evidence of chronic nasal irritation and inflammation and ocular injury (including retinal degeneration, corneal irritation, uveitis and corneal damage) has been documented in rats exposed to 150 ppm, 6 hours/day, 5 days/week for 104 weeks. Earlier reports linking exposure to morpholine with an increased incidence of hepatocellular carcinoma and pulmonary angiosarcoma, probably resulted from exposure to the carcinogenic contaminant, N-nitrosomorpholine. It must be noted, however, that there is a potential to convert morpholine, a secondary amine), in the body, to the potentially carcinogenic N-  nitros-morpholine. N-nitroso-compounds represent a major class of important chemical carcinogens and mutagens. The induction of tumours by single doses of these substances testify to their potency. Whilst it is difficult to extrapolate animal carcinogenicity data to humans, such data strongly suggests that these compounds are human carcinogens. As a rule the N-nitrosamines as a group are carcinogenic in a multitude of organs and tissues. This is also true for the individual N-nitrosamines where the tumour localisation does not depend only on the kind of nitrosamine but also the species and dose. Mostly, however, a preferred target organ (or even several) can be identified. This is frequently the liver.