Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

PRODUCT NAME

JUROX NEOMYCIN SULFATE INJECTION

NFPA

PRODUCT USE

Injection for the treatment of infections due to susceptible organisms in dogs, cats,
horses, cattle, sheep and pigs

Section 2 - HAZARDS IDENTIFICATION

CANADIAN WHMIS SYMBOLS

EMERGENCY OVERVIEW

RISK

POTENTIAL HEALTH EFFECTS

ACUTE HEALTH EFFECTS

SWALLOWED

  The material has NOT been classified as "harmful by ingestion". This is because of the lack of corroborating animal or human evidence. The material may still be damaging to the health of the individual, following ingestion, especially where pre-existing organ (e.g. liver, kidney) damage is evident. Present definitions of harmful or toxic substances are generally based on doses producing mortality (death) rather than those producing morbidity (disease, ill-health). Gastrointestinal tract discomfort may produce nausea and vomiting. In an occupational setting however, unintentional ingestion is not thought to be cause for concern.  

EYE

  Although the liquid is not thought to be an irritant, direct contact with the eye may produce transient discomfort characterized by tearing or conjunctival redness (as with windburn).  

SKIN

  There is some evidence to suggest that this material can cause inflammation of the skin on contact in some persons.  Skin contact is not thought to have harmful health effects, however the material may still produce health damage following entry through wounds, lesions or abrasions.  Entry into the blood-stream, through, for example, cuts, abrasions or lesions, may produce systemic injury with harmful effects. Examine the skin prior to the use of the material and ensure that any external damage is suitably protected.  The material may cause skin irritation after prolonged or repeated exposure and may produce on contact skin redness, swelling, the production of vesicles, scaling and thickening of the skin.  

INHALED

  Not normally a hazard due to non-volatile nature of product.  The material is not thought to produce adverse health effects or irritation of the respiratory tract (as classified using animal models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable control measures be used in an occupational setting.  

CHRONIC HEALTH EFFECTS

  Limited evidence suggests that repeated or long-term occupational exposure may produce cumulative health effects involving organs or biochemical systems.  There is limited evidence that, skin contact with this product is more likely to cause a sensitization reaction in some persons compared to the general population.  Long-term exposure to aminoglycoside antibiotics (such as gentamicin) can damage the kidneys and malabsorption with a fatty, foul-smelling diarrhea. In some patients, there may be hearing loss and damage to the balancing system, after topical application or injection. Respiratory depression and paralysis of muscle has also been caused by this class of antibiotic. Some patients may display visual hallucinations, multiple nerve disorders and brain damage. Especially in those patients receiving cancer chemotherapy, there may be electrolyte imbalance in the blood following long-term use (reduced magnesium, calcium and potassium).  After either injection, skin contact swallowing, p-hydroxybenzoates can cause allergic reactions. Cross-sensitivity occurs between different species. Symptoms include narrowing of the airways, skin rashes with blistering, severe wheals, runny nose and blurred vision. There may be an anaphylactic reaction. Prolonged exposure to salicylates (o-  hydroxybenzenes) can damage the kidney and pancreas. Asthmatics are very prone to developing hypersensitivity to salicylates, with signs such as itchy rashes, other skin eruptions, blocked nose, narrowed airways and shortness of breath. This may cause death.  Sensitization may result in allergic dermatitis responses includingrash, itching, hives or swelling of extremities.