Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

PRODUCT NAME

HACH NITRITE STANDARD SOLUTION 250 UG/L AS NO2-N

NFPA

PRODUCT USE

Standard solution.

Section 2 - HAZARDS IDENTIFICATION

CANADIAN WHMIS SYMBOLS

EMERGENCY OVERVIEW

RISK

May cause CANCER.
Harmful to aquatic organisms.

POTENTIAL HEALTH EFFECTS

ACUTE HEALTH EFFECTS

SWALLOWED

  Accidental ingestion of the material may be damaging to the health of the individual.  

EYE

  Although the liquid is not thought to be an irritant, direct contact with the eye may produce transient discomfort characterized by tearing or conjunctival redness (as with windburn).  

SKIN

  The material is not thought to produce adverse health effects or skin irritation following contact (as classified using animal models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable gloves be used in an occupational setting.  Entry into the blood-stream, through, for example, cuts, abrasions or lesions, may produce systemic injury with harmful effects. Examine the skin prior to the use of the material and ensure that any external damage is suitably protected.  

INHALED

  Inhalation may produce health damage*.  The material is not thought to produce respiratory irritation (as classified using animal models). Nevertheless inhalation of vapors, fumes or aerosols, especially for prolonged periods, may produce respiratory discomfort and occasionally, distress.  Inhalation of vapors or aerosols (mists, fumes), generated by the material during the course of normal handling, may be damaging to the health of the individual.  

CHRONIC HEALTH EFFECTS

  There is ample evidence that this material can be regarded as being able to cause cancer in humans based on experiments and other information.  There is some evidence that human exposure to the material may result in developmental toxicity. This evidence is based on animal studies where effects have been observed in the absence of marked maternal toxicity, or at around the same dose levels as other toxic effects but which are not secondary non-specific consequences of the other toxic effects.  Exposure to sodium nitrite in drinking water resulted in an increased incidence of epithelial hyperplasia in the forestomach of male and female rats and in the glandular stomach of male mice.There was equivocal evidence of carcinogenic activity of sodium nitrite in female B6C3F1 mice based on the positive trend in the incidences of squamous cell papillomas or carcinomas (combined) of the forestomach. There was no evidence of carcinogenic activity in male and female F344/N rats or B6C3F1 male mice exposed to 750, 1500 or 3000 ppm.  NTP Technical Report Series No. 495, May 2001Under certain conditions, nitrites can react with secondary amines, either alone or in biological systems, to form carcinogenic nitrosamines.Sodium nitrite (60 mg/kg) administered in drinking water to pregnant guinea pigs produced maternal anaemia and increased the incidences of abortion and foetal mortality. Administration of 2000-3000 mg/l sodium nitrite in drinking water, to pregnant rats, produced 30-53% foetal mortality. In rat dams given 0.025-0.5% in feed, sodium nitrite caused an increase in foetal and pup mortality and decreases in pre-weanling body weights.