Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

PRODUCT NAME

UOP AMINE GUARD INHIBITOR A

NFPA

PRODUCT USE

As a mordant in the textile and leather industries; for therapeutic use and as a reagent.

SYNONYMS

C4-H4-O7-Sb-K, "[as described in British Pharmacopoeia]", C2-H2-(OH)2-(COOK)-CO2-(SbO),
C8-H4-K2-O12-Sb2, "[as described in US Pharmacopoeia]", "antimonyl potassium tartrate",
"potassium acid antimony tartrate", "potassium antimonyl tartrate", "tartarised antimony",
"tartarated antimony", "tartaric acid, antimony potassium salt", "tartar emetic"

Section 2 - HAZARDS IDENTIFICATION

CANADIAN WHMIS SYMBOLS

EMERGENCY OVERVIEW

RISK

Toxic if swallowed.

POTENTIAL HEALTH EFFECTS

ACUTE HEALTH EFFECTS

SWALLOWED

  Toxic effects may result from the accidental ingestion of the material; animal experiments indicate that ingestion of less than 40 gram may be fatal or may produce serious damage to the health of the individual.  GOSSELIN, SMITH & HODGE: Clinical Toxicology of Commercial Products, 5th Ed.  

EYE

  Although the material is not thought to be an irritant, direct contact with the eye may produce transient discomfort characterized by tearing or conjunctival redness (as with windburn).  The dust may produce eye discomfort causing smarting, pain and redness.  

SKIN

  The material is not thought to produce adverse health effects or skin irritation following contact (as classified using animal models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable gloves be used in an occupational setting.  Open cuts, abraded or irritated skin should not be exposed to this material.  

INHALED

  The material is not thought to produce adverse health effects or irritation of the respiratory tract (as classified using animal models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable control measures be used in an occupational setting.  Persons with impaired respiratory function, airway diseases and conditions such as emphysema or chronic bronchitis, may incur further disability if excessive concentrations of particulate are inhaled.  

CHRONIC HEALTH EFFECTS

  The most likely routes of exposure are via inhalation of dust and  skin and eye contact.  The compound is used medicinally, but therapeutic dose is close to the  toxic dose. Periodic medical examinations covering lungs, skin,  nervous system, heart and gastro-intestinal tract are recommended for  occupationally exposed workers.       [ILO Encyclopaedia]  The trivalent antimony compounds are cardiotoxic. Collapse and sudden  death due to anaphylactic-type reactions have occurred. Therapeutic doses  given intravenously cause nausea, vomiting, cough and abdominal pain and  diarrhoea. Other side-effects include anorexia, chest, muscle and joint  pains, pruritus, skin rashes, dizziness and oedema.  The material may accumulate in the human body and progressively causetissue damage.  Renal and hepatic damage occur rarely and haemolytic anaemia has been  reported. Continuous treatment with small doses of antimony may give rise  to subacute poisoning similar to chronic arsenic poisoning.