Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

PRODUCT NAME

JOHNSONS ORTHOXICOL HEADCOLD CAPLETS

NFPA

PRODUCT USE

Analgesic, antipyretic and nasal decongestant. Used for temporary relief of the following
symptoms of head cold - headaches, body aches and pains, runny nose and fever. Recommended
Dosage: Adults and children over 12 years: 2 caplets four times daily. Not to be
administered to children under 12 unless directed by a doctor.

SYNONYMS

"4-acetamidophenol / pseudoephedrine hydrochloride", "4-acetamidophenol / pseudoephedrine
hydrochloride"

Section 2 - HAZARDS IDENTIFICATION

CANADIAN WHMIS SYMBOLS

EMERGENCY OVERVIEW

RISK

POTENTIAL HEALTH EFFECTS

ACUTE HEALTH EFFECTS

SWALLOWED

  Not considered an irritant through normal use.  

EYE

  Not applicable.  

SKIN

  Skin contact with the material may damage the health of the individual; systemic effects may result following absorption.  Not applicable.  

INHALED

  Not applicable.  

CHRONIC HEALTH EFFECTS

  Principal route of exposure is usually by ingestion.  The material may accumulate in the human body and progressively causetissue damage.  A small fraction of an ingested dose may be metabolically activated in the  liver and in the kidney to a form that reacts covalently with tissue  nucleophiles. Toxic doses of the drug presumably deplete liver stores of  reduced glutathione and the metabolite is then free to react with essential  tissue macromolecules resulting in cell death and necrosis.