LAURYL GLUCETH-10 HYDROXYPROPYL DIMONIUM CHLORIDE
Flammability | 1 | |
Toxicity | 2 | |
Body Contact | 3 | |
Reactivity | 1 | |
Chronic | 0 | |
SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4 |
Used in cosmetics.
"lauryl methyl gluceth-10 hydroxypropyl dimonium chloride", "ethoxylated (10 moles)
methyl glucoside hydroxypropyl dimethyldodecyl ammonium chloride", estquat, "cationic
polyol"
Harmful if swallowed.
Irritating to skin.
Risk of serious damage to eyes.
Toxic to aquatic organisms.
Accidental ingestion of the material may be harmful; animal experiments indicate that ingestion of less than 150 gram may be fatal or may produce serious damage to the health of the individual. Concentrated solutions of many cationics may cause corrosive damage to mucous membranes and the esophagus. Nausea and vomiting (sometimes bloody) may follow ingestion. Serious exposures may produce an immediate burning sensation of the mouth, throat and abdomen with profuse salivation, ulceration of mucous membranes, signs of circulatory shock (hypotension, labored breathing, and cyanosis) and a feeling of apprehension, restlessness, confusion and weakness. Weak convulsive movements may precede central nervous system depression. Erosion, ulceration, and petechial hemorrhage may occur through the small intestine with glottic, brain and pulmonary edema. Death may result from asphyxiation due to paralysis of the muscles of respiration or cardiovascular collapse. Fatal poisoning may arise even when the only pathological signs are visceral congestion, swallowing, mild pulmonary edema or varying signs of gastrointestinal irritation. Individuals who survive a period of severe hypertension may develop kidney failure. Cloudy swelling, patchy necrosis and fatty infiltration in such visceral organs as the heart, liver and kidneys shows at death.
If applied to the eyes, this material causes severe eye damage. Many cationic surfactants are very irritating to the eyes at low concentration. Concentrated solutions can cause severe burns with permanent clouding.
Skin contact is not thought to have harmful health effects, however the material may still produce health damage following entry through wounds, lesions or abrasions. This material can cause inflammation of the skin oncontact in some persons. The material may accentuate any pre-existing dermatitis condition. Entry into the blood-stream, through, for example, cuts, abrasions or lesions, may produce systemic injury with harmful effects. Examine the skin prior to the use of the material and ensure that any external damage is suitably protected. Cationic surfactants cause skin irritation, and, in highconcentrations, caustic burns.
The material is not thought to produce either adverse health effects or irritation of the respiratory tract following inhalation (as classified using animal models). Nevertheless, adverse effects have been produced following exposure of animals by at least one other route and good hygiene practice requires that exposure be kept to a minimum and that suitable control measures be used in an occupational setting. Not normally a hazard due to non-volatile nature of product.
Long-term exposure to the product is not thought to produce chronic effects adverse to the health (as classified using animal models); nevertheless exposure by all routes should be minimized as a matter of course. Bsed on experimental results esterquats are unlikely to be significant human allergens. Animal studies indicate a nephrotoxic potential by this route.