Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

PRODUCT NAME

VASICINE

NFPA

PRODUCT USE

Expectorant. Quinaline alkaloid isolated from Adhatoda vasica Nees, Acanthaceae and
Peganum harmala L., Zygophyllaceae.

SYNONYMS

C11-H10-N2-O, "pyrrolo[2, 1-b]quinazolin-3-ol, 1, 2, 3, 9-tetrahydro-", "pyrrolo[2, 1-
b]quinazolin-3-ol, 1, 2, 3, 9-tetrahydro-", peganine, vasicin, "quinazoline alkaloid",
expectorant

Section 2 - HAZARDS IDENTIFICATION

CANADIAN WHMIS SYMBOLS

EMERGENCY OVERVIEW

RISK

Harmful if swallowed.

POTENTIAL HEALTH EFFECTS

ACUTE HEALTH EFFECTS

SWALLOWED

  Accidental ingestion of the material may be harmful; animal experiments indicate that ingestion of less than 150 gram may be fatal or may produce serious damage to the health of the individual.  

EYE

  Although the material is not thought to be an irritant, direct contact with the eye may produce transient discomfort characterized by tearing or conjunctival redness (as with windburn).  

SKIN

  The material is not thought to produce adverse health effects or skin irritation following contact (as classified using animal models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable gloves be used in an occupational setting.  Toxic effects may result from skin absorption.  

INHALED

  Inhalation may produce health damage*.  The material is not thought to produce respiratory irritation (as classified using animal models). Nevertheless inhalation of the material, especially for prolonged periods, may produce respiratory discomfort and occasionally, distress.  Persons with impaired respiratory function, airway diseases and conditions such as emphysema or chronic bronchitis, may incur further disability if excessive concentrations of particulate are inhaled.  

CHRONIC HEALTH EFFECTS

  Principal routes of exposure are by accidental skin and eye contact andinhalation of generated dusts.  No human exposure data available. For this reason health effects described are based on experience with chemically related materials.  The material may accumulate in the human body and progressively causetissue damage.