UNIROYAL TERRACLOR 75WP
Flammability | 1 | |
Toxicity | 2 | |
Body Contact | 1 | |
Reactivity | 0 | |
Chronic | 2 | |
SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4 |
Soil fungicide and seed dressing agent. Uses include damping- off of cotton; black root
and club root of cabbage, cauliflower, Brussel sprouts and broccoli; scab and
Rhizoctoniaof potatoes.
"75-WP Pesticide", "75-WP Pesticide", PCNB, pentachloronitrobenzene, fungicide,
"quintozene containing pesticide"
Harmful if swallowed.
May cause SENSITIZATION by skin contact.
Harmful: danger of serious damage to health by prolonged exposure through
inhalation.
Very toxic to aquatic organisms, may cause long- term adverse effects in the
aquatic environment.
Accidental ingestion of the material may be harmful; animal experiments indicate that ingestion of less than 150 gram may be fatal or may produce serious damage to the health of the individual. Considered an unlikely route of entry in commercial/industrial environments.
Although the material is not thought to be an irritant, direct contact with the eye may produce transient discomfort characterized by tearing or conjunctival redness (as with windburn).
The material is not thought to produce adverse health effects or skin irritation following contact (as classified using animal models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable gloves be used in an occupational setting. Sensitization may result in allergic dermatitis responses includingrash, itching, hives or swelling of extremities.
The material is not thought to produce adverse health effects or irritation of the respiratory tract (as classified using animal models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable control measures be used in an occupational setting. Persons with impaired respiratory function, airway diseases and conditions such as emphysema or chronic bronchitis, may incur further disability if excessive concentrations of particulate are inhaled. The material presents a hazard from repeated exposures.
Skin contact with the material is more likely to cause a sensitization reaction in some persons compared to the general population.
The principle routes of exposure are via inhalation and skin contact. PCNB (parachloronitrobenzene) has been administered orally and subcutaneously to pregnant mice and rats where it has been found to produce both birth deformities and fetal deaths. Other adverse effects demonstrated in animals following exposure include liver and kidney toxicity, inhibition of weight gain, ovarian abscecces and hepatomas. These effects may be entirely due to the level of contaminating hexachlorobenzene found in the commercial product. In a study designed to investigate the cancer-causing potential of the substance an unexpected side-effect, namely a increased susceptibility to bacterial infection was evident amongst mice. The substance is metabolised in the liver where it is conjugated with glutathione to form pentachloroaniline; both the substance and its metabolites are eliminated rapidly in urine and faeces with some bioaccumulation in lipid rich tissues of the body. Oral administration of the substance in cats (1600 mg/kg in corn oil carrier) was effective in producing methemoglobin concentrations of 11% (against 1% in controls) and in producing an eight-fold increase in erythroctes containing Heinz bodies.