KEITH HARRIS CITRAL NATURAL
Flammability | 0 | |
Toxicity | 2 | |
Body Contact | 2 | |
Reactivity | 0 | |
Chronic | 2 | |
SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4 |
Flavouring agent; perfume.
Irritating to skin.
May cause SENSITIZATION by skin contact.
HARMFUL - May cause lung damage if swallowed.
Although ingestion is not thought to produce harmful effects, the material may still be damaging to the health of the individual following ingestion, especially where pre- existing organ (e.g. liver, kidney) damage is evident. Present definitions of harmful or toxic substances are generally based on doses producing mortality (death) rather than those producing morbidity (disease, ill-health). Gastrointestinal tract discomfort may produce nausea and vomiting. In an occupational setting however, ingestion of insignificant quantities is not thought to be cause for concern. Essential oils cause mild irritation of the mouth if taken orally, causing more saliva to be produced and a warm feeling. Large amounts affect the digestive system causing nausea, vomiting and diarrhea. Sometimes urination may be affected, causing difficulty or pain in urinating, reduced urine output, blood in the urine, unconsciousness and shallow breathing. Lung swelling and inflammation are possible complications. Stupor, excitement and respiratory failure may result, as well as convulsions; the central nervous system may either be depressed or stimulated. The kidneys may be damaged, and swelling and severe clogging can occur in the lungs, skin and kidneys. Essential oils increase the rate of miscarriage, but in low doses do not usually cause an abortion. An estimated acceptable daily intake of up to 500 microgram per kilogram body weight was estimated for the terpene/ terpenoids, citral, geranyl acetate, citronellol, linalool and linaly acetate (expressed as citral). Twenty-third Report of the Joint FAO/WHO Expert Committee on Food Additives Tech. Rep. Ser. Wld Hlth Org. No. 648, 1980.
Although the material is not thought to be an irritant, direct contact with the eye may produce transient discomfort characterized by tearing or conjunctival redness (as with windburn). Precautions for handling reactive unsaturated aldehydes should be the same as for those of highly active eye and pulmonary irritants such as phosgene. Sufficient engineering controls, with monitoring where possible, are of importance.
This material can cause inflammation of the skin oncontact in some persons. Skin contact is not thought to have harmful health effects, however the material may still produce health damage following entry through wounds, lesions or abrasions. Essential oils irritate the skin and redden it, causing at first warmth and smarting, followed by some local loss of sensation. They have been used to treat chronic inflammatory conditions and to relieve neuralgia and rheumatic pain. Care should be taken to avoid blistering; these oils may also produce sensitization. The material may cause severe skin irritation after prolonged or repeated exposure and may produce on contact skin redness, swelling, the production of vesicles, scaling and thickening of the skin. Repeated exposures may produce severe ulceration.
Inhalation may produce health damage*. The material is not thought to produce respiratory irritation (as classified using animal models). Nevertheless inhalation of the material, especially for prolonged periods, may produce respiratory discomfort and occasionally, distress. Inhalation of essential oil volatiles may cause dizziness, rapid, shallow breathing, increased heart rate, respiratory irritation, loss of consciousness or convulsions. Urination may stop, and there may be swelling and inflammation of the lungs. Inhalation of quantities of liquid mist may be extremely hazardous, even lethal due to spasm, extreme irritation of larynx and bronchi, chemical pneumonitis and pulmonary edema. Exposure to aldehydes causes neurological symptoms such as headache, drowsiness, dizziness, seizures, depression and coma. Cardiovascular involvement may result in increased heart rate, collapse and low blood pressure; respiratory effects include throat spasms, irritation, difficulty swallowing, pulmonary edema and an asthma-like condition. Gastrointestinal signs include nausea, blood in vomit, diarrhea, ulcers and abdominal pain. Massive exposures may damage the kidney and liver.
Skin contact with the material is more likely to cause a sensitization reaction in some persons compared to the general population.
Principal routes of exposure are by accidental skin and eye contact and by inhalation of vapors especially at higher temperatures. No human exposure data available. For this reason health effects described are based on experience with chemically related materials. As with any chemical product, contact with unprotected bare skin; inhalation of vapor, mist or dust in work place atmosphere; or ingestion in any form, should be avoided by observing good occupational work practice.